Stratum granulosum is a well defined region of epidermis found under the lucidum layer in the palms and soles and under corneum in the other areas of the skin.
Definition of stratum granulosumStratum granulosum is defined as "the layer of epidermis just under the stratum corneum or (on the palms and soles) just under the stratum lucidum; contains cells (with visible granules) that die and move to the surface." by wordnetweb.princeton.edu/perl/webwn.
Structure and function of stratum granulosum
These squamous cells have many basophilic granules called keratohyalin granules which are small and are not bound by membrane. Filaggrin, a type of protein, is found in large quantities in theses cells and is believed to bundle keratin. Lipid containing lamellar granules are present which are bound by membrane. These membrane-bound granules secrete the contents to extracellular space by exocytosis (peni-cytosis) and give rise to sheets of waterproof fatty barrier. This barrier function also prevent nutrients diffusion from the lower cells, leading to death of cells.
Interesting topics in dynamic skin care:
- Reticular dermis.
- Definition and function of hypodermis.
- Skin sensitive to touch.
- Different type of face skin.
- Main functions of human skin.
- Know your skin.
- Nourishing skin with fruits and vegetables.
- Small itchy water blisters on hands and feet.
- Cosmetic laser treatments - Types of cosmetic lasers.
- What are salmon patches? - Nevus simplex birthmarks on babies.
1.Harding, C. R. (2004), The st. corneum: structure and function in health and disease. Dermatologic Therapy, 17: 6–15. doi: 10.1111/j.1396-0296.2004.04S1001.x
Image source: http://en.wikipedia.org/wiki/File:Skinlayers.png
License: Public domain
Current topic in dynamic skin care: Stratum granulosum layer - Definition and function